Researcher

A 9 month 100 % position as a r esearcher is vacant. Drug development, B cell malignanc y, Department of Immunology, Oslo University Hospital.

The researcher will work on an ongoing project investigating the efficacy of a drug candidate targeting a B cell malignancy. The project will be led by prof. Ludvig A. Munthe at the Department of Immunology, Oslo University Hospital and RCN CoE PRIMA, University of Oslo. The project is funded by the RCN and a Biotech company in collaboration with the Munthe group. The research group is part of a stimulating and international research environment of about 100 scientists working on various aspects of immunology.

Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!

Duties and responsibilities

The candidate will contribute to mechanistic studies and efficacy of a lead drug candidate targeting a B cell malignancy, effect on pathogenic B-cell clones, generation of preclinical data, and translational analyses linking immune phenotypes to therapeutic response, as well as designing assays to investigate drug synergies, and characterization of potential off-target effects.

Qualifications

We seek a highly motivated candidate with a PhD or equivalent degree in immunology, molecular biology, hematology, or a related biomedical discipline.

The ideal candidate will have:

• Documented research experience in B-cell malignancies.
• A strong background in B-cell biology, including B-cell culture systems, functional assays, and immunophenotyping using multicolor flow cytometry.
• Experience in development and preclinical testing of targeted therapies or biologics.
• Experience with xenograft models of B-cell lymphoproliferative disease and in vivo experimental systems and in handling mice (FELASA C approval) would be an advantage.
• Solid understanding of translational immunology, including mechanisms linking tumor immunology and drug efficacy.
• Experience in data analysis and interpretation of complex immunological datasets.

Application
All applicants must apply through WebCruiter and include:

• Application letter
• CV summarizing all relevant experience
• Full list of publications
• Copies of educational certificates and transcripts of records
• Names and contact details of 2-3 references (include brief information of relation)

The application letter and CV should be in English or in a Scandinavian language. All other documents may be submitted in English, German, French, Italian or a Scandinavian language. In the evaluation of the applications, an emphasis will be placed on the applicant's academic and personal qualifications, good cooperative skills, and the ability to successfully join a research team.

Personal qualities

• Highly motivated and detail-oriented
• Good problem-solving skills
• Ability to work as part of a team
• Proficiency in English
• Good writing skills

We can offer:

• An exciting and vibrant international scientific environment.
• Potential for personal and scientific growth.
• Membership in the Norwegian pension fund.
• Possibility of extension depending on funds.